TRIMEBOSTON 300

DOSAGE 

Adults: The usual dosage is 300 mg/day and can be increased exceptionally up to 600 mg/day.

Recommended duration of use is 3 days. In the absence of any warning sign, the maximum duration of use will be 7 days.

ADMINISTRATION

TRIMEBOSTON 300 is administered orally.

CONTRADICATIONS

Hypersensitivity to the active substance or to any of the excipients mentioned.

WARNINGS AND PRECAUTIONS

This medicine contains lactose. Its use is not recommended in patients with galactose intolerance, Lapp lactase deficiency or glucose or galactose malabsorption syndrome (rare hereditary diseases).

INTERACTIONS 

Not applicable.

PREGNANCY AND LACTATION

Pregnancy 

Studies in animals have not shown any teratogenic effect.

There are currently no sufficiently relevant data to evaluate a possible malformative or fetotoxic effect of trimebutine when administered during pregnancy.

Therefore, as a precautionary measure, it is preferable not to use trimebutine during the first trimester of pregnancy. In the absence of adverse effects expected for the mother or child, use of trimebutine during the second and third trimesters of pregnancy should be considered only when necessary.

Lactation 

The passage into the breast milk of trimebutine is not known.

As a precautionary measure, it is preferable to avoid using trimebutine during breast-feeding.

UNDESIRABLE EFECTS

Frequency are defined as: very common (≥1 / 10), common (≥1 / 100 to <1/10), uncommon (≥1 / 1000 to <1/100), rare (≥1 / 10000 to <1/1000), very rare (<1/10000); indeterminate frequency (can not be estimated from the available data).

OVERDOSE AND TREATMENT

Symptoms

In case of overdose, bradycardia-type cardiac disorders, QTc prolongation, or tachycardia and neurological disorders such as somnolence, convulsion and coma could be observed. 

Treatment 

Surveillance in specialized settings is necessary and symptomatic treatment should be implemented.

STORAGE CONDITION 

In a dry place, below 30 °C, protect from light.

SHELF- LIFE 

36 months from the manufacturing date. Do not use after the expiry date.