Paralmax Pain

POSOLOGY, METHOD OF ADMINITRATION

For oral administration.

Posology:

Adults: 1-2 tablets x 3 times/day.

Chronic case: 1 tablet x 3 times/day.

CONTRAINDICATIONS

In patients with a known hypersensitivity to any ingredient of the drug. In patients with a history of hypersensitivity reactions e.g. bronchospasm, angioedema, asthma, rhinitis, or urticaria associated with acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs).

The patients had advanced peptic ulcer disease, liver failure, severe renal failure, congestive heart failure, nasal polyps, asthma, and third-trimester pregnancy. Children < 18 years.

People who have blood clotting problems or are being treated with coumarin anticoagulants.

In concomitant use with Paracetamol-containing products – increased risk of serious adverse effects.

PRECAUTIONS FOR USE

Ibuprofen:

Ibuprofen should be used with caution in patients with a history of gastrointestinal ulceration and endogenous coagulopathy.

Cardiovascular Thrombotic Risk:

Systemic nonsteroidal anti-inflammatory drugs (NSAIDs), other than aspirin, cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur during the first few weeks of treatment and may increase with the duration of use. The increase in cardiovascular thrombotic risk has been observed most consistently at higher doses.

- Physicians should periodically evaluate the occurrence of cardiovascular events, even in the absence of previous cardiovascular symptoms. Patients should be informed about the symptoms of serious cardiovascular events and see a doctor immediately when these symptoms appear.

- Undesirable effects may be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms.

Paracetamol:

Neutropenia and thrombocytopenic purpura have occurred with paracetamol.

People with phenylketonuria - urine and people who have to limit the amount of phenylalanine put into the body must be careful when using some paracetamol containing aspartame, which will be converted in the stomach - intestines into phenylalanine after taking.

Patients with asthma may experience hypersensitivity reactions to paracetamol-containing sulfites.

Paracetamol should be used with caution in patients with pre-existing anemia, as cyanosis may not be evident, despite dangerously high concentrations of methemoglobin in the blood.

Alcohol should be avoided and limited because heavy drinking can increase the hepatotoxicity of paracetamol.

Using with caution in people with impaired liver or kidney function.

Physicians should warn patients about signs of serious skin reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) or Lyell's syndrome, generalized exanthematous pustulosis acute trunk (AGEP).

SHELF LIFE: 36 months from the manufacturing date. Do not use after the expiry date.