Paracetamol Boston 500

POSOLOGY AND METHOD OF ADMINISTRATION

Posology 

Paracetamol Boston 500 is for oral use.

Method of administration

Adults, elderly, and children over 12 years: 1-2 tablets every 4-6 hours. Maximum dose of 8 tablets in 24 hours.

Children 6-12 years: ½ - 1 tablet every 4-6 hours. Maximum dose of 4 tablets in 24 hours. 

Children under 6 years of age: Use other suitable dosage forms

Patients with renal failure:

Adults:

● Clcr < 10 ml/min: Dosing interval should be at least 8 hours

● 10 ml/min ≤ Clcr ≤ 50 ml/min: Dosing interval should be at least 6 hours 

Children:

● Clcr < 10 ml/min: Dosing interval should be at least 8 hours

Patients with hepatic impairment: Use with caution. Use low doses. Avoid prolonged use

CONTRAINDICATIONS

Hypersensitivity to any ingredient of the drug.

Patients with G6PD deficiency.

WARNINGS AND PRECAUTION

Conditions need to be cautious when taking this medication

Caution is advised in the administration of paracetamol to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.

Do not exceed the recommended dose.

Do not take for more than 3 days without consulting a doctor.

Do not take with any other paracetamol-containing products.

Patients should consult a doctor if they have arthritis that is not severe and requires daily pain relievers

Immediate medical advice should be sought in the event of an overdose, even if you feel well, because of the risk of delayed, serious liver damage.

Physicians should warn patients about signs of severe skin reactions such as Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), Lyell's syndrome, acute generalized exanthematous pustulosis (AGEP)

Recommendations for pregnant and lactating women

Pregnancy: Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage, but patients should follow the advice of their doctor regarding its use

Breastfeeding: Paracetamol is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breastfeeding.

Effects of drugs on work (machine operator, driving a train, people working at height, and other cases)

Paracetamol does not influence the ability to drive and use machines.

SHELF-LIFE

36 months from the manufacturing date. Do not use after the expiry date